The newspaper said that Alamance County sheriff's deputies began dismantling a sound system and telling the crowd of demonstrators to disperse as people were giving speeches.
Several arrests were made outside Alamance County's courthouse as police tried to disperse the protesters and police used pepper spray on some people, including children, the Raleigh News & Observer newspaper said.
US President Donald Trump's challenger, Democratic presidential nominee Joe Biden, narrowly leads in North Carolina by 0.7 percent, according to the most recent polls.
On Friday, Trump slammed the US Supreme Court's decision to allow a six-day deadline extension for the receipt of mail-in ballots in North Carolina, up until November 12. The Supreme Court rejected a second bid from the Republican Party to block the deadline extension on Thursday.