Protein That Can Stop Cancer Identified
Umer Jamshaid Published March 22, 2018 | 11:48 PM
Researchers have discovered a protein that prevents the uncontrolled proliferation of cancer cells in the liver. The anti-cancer protein, called LHPP, can also serve as a biomarker for the diagnosis and prognosis of liver cancer, said the study published in the journal Nature.
ISLAMABAD, (UrduPoint / Pakistan Point News - 22nd Mar, 2018 ) :Researchers have discovered a protein that prevents the uncontrolled proliferation of cancer cells in the liver. The anti-cancer protein, called LHPP, can also serve as a biomarker for the diagnosis and prognosis of liver cancer, said the study published in the journal Nature.
The incidence of liver cancer, also known as hepatocellular carcinoma, is usually diagnosed at a very late stage when the liver is already severely damaged and hence overall prognosis is poor. The researchers believe that detection of the anti-cancer protein LHPP as a biomarker may allow clinicians to provide better treatment options.
"It is striking that LHPP is present in healthy tissue and completely absent in tumour tissue," said first author Sravanth Hindupur from University of Basel in Switzerland.
In the study conducted in a mouse model for hepatocellular carcinoma, the researchers analysed a total of more than 4,000 proteins, comparing them in healthy and tumour tissue.
The research showed that LHPP emerged as the top favourite. Re-introduction of the genetic information for LHPP by the researchers was found to prevent the formation of tumours and maintain liver function. "Similar to the mouse model, we also saw a striking decrease in LHPP levels in tumours of patients with liver cancer," Hindupur said.
Recent Stories
Zhao Shirin calls on Punjab Industries Minister
Immunization campaign to protect children from deadly diseases in full swing
Action taken against officers not recovering 85% tax: Secretary
Haiti transitional council sworn in after months of violence
IHC adjourns cipher case hearing against PTI founder till April 20,
Ukrainian village battles mines year after Russia forced out
Collective efforts needed to curb terrorism: Barrister Saif
China's Shenzhou-18 mission takes off bound for space station
Police arrest 4 suspects, recovered phones, bikes
Thousands of flights scrapped as French air traffic controllers strike
WWB directed to identify board’s land for revenue generation
Poverty to be ended by establishing border markets: Balochistan Governor
More Stories From Health
-
Vaccines save at least 154 million lives in 50 years: WHO
1 day ago -
UHS to issue MBBS degrees within three months after final result
1 day ago -
Rawalpindi woman gives birth to six babies
6 days ago -
DC calls for intensive anti-polio drive in ICT
7 days ago -
World Hemophilia Day observed to underscore importance of providing comprehensive care
8 days ago -
Six in a family with heart on the 'right side'
8 days ago
-
Diabetic disease increasing rapidly : Dr. Noor Elahi Memon
8 days ago -
World Hemophilia Day observed
8 days ago -
ATC dismisses bail petition of doctor involved in illegal kidneys transplant
16 days ago -
Dr. Shehzad warns against deviation from WHO guidelines on anti-smoking
16 days ago -
Health activists express concerns over attempts to derail tobacco control
18 days ago -
UHS declares MBBS first prof, MS urology exam results
27 days ago